Projects per year
Personal profile
Personal profile
Minyan Wang, Professor at Department of Biosciences and Bioinformatics, School of Science, XJTLU, Director of Centre for Neuroscience jointly founded by Wangwenli Charitable Foundation and XJTLU; She holds an honorary staff position at the University of Liverpool and is PhD supervisor at the Institute of Systems, Molecular & Integrative Biology, University of Liverpool, UK. Prior to XJTLU, she held a lecturer position at the School of Pharmacy and Biomedical Sciences, University of Central Lancashire, UK between 2008-2011, after the two postdoctoral training at University of Newcastle and University of Bradford, UK, During 2004-2008. She was awarded of PhD in Neuropharmacology in 2004 at University of Bradford, UK, and obtained 1st degree in Pharmacy in 1988 and MSc in Pharmacology in 1997 at Hebei Medical University. She holds an MA degree in teaching an learning in Higher Education, UK and has rich experience in curriculum design and development in Higher Education. Additionally, she had worked at a subsector of SFDA on drug evaluation and pharmacological and toxicogical studies in the areas of neurological diseases, diabetes and cancer in her early career. She is a member of International Headache Society and committee member of Chinese Headache Society.
Research interests
Over a distinguished thirty-year career, Professor Wang has dedicated herself to addressing neurology's most formidable challenges, including migraine, ischemia, epilepsy, and aging. Her most significant contributions are in migraine, where her pioneering research into disease mechanisms has been instrumental in identifying and validating novel therapeutic targets. Her laboratory is uniquely equipped with a advanced research platform, utilizing multimodal ex vivo and in vivo models that accurately simulate the neurovascular coupling central to disease pathology. This powerful system, integrating techniques like microdialysis, intrinsic optical imaging, electrophysiology, and laser Doppler flowmetry, allows her team to interrogate intricate disease mechanisms and validate promising drug candidates with exceptional precision. Leading many projects with international collaborations, her work has advanced the understanding of the signaling pathways involved in the pathogenesis of migraines, serving as a foundation for drug target identification. These include researching membrane receptors, calcitonin gene-related Peptide (CGRP), stress-sensing cation channel TRPA1 and intracellular kinases involved in central and trigeminovascular system sensitization. The findings addressed how these signals sensitize the CNS and trigeminovascular system for migraine pain transmission. She has enriched academic literature with over 40 scholarly papers and book chapters.
More details about her publications can be also found via the URL (https://www.researchgate.net/profile/Minyan_Wang).
Professor Wang cordially invite passionate Ph.D. candidates with an interest in neuroscience to apply for our projects.
Experience
Lecturer/Associate Professor/Senior Associate Professor/Professor, XJTLU, 2011 to present
Lecturer, School of Pharmacy and Biomedical Sciences, University of Central Lancashire - 2008 to 2010
Senior Pharmacologist and ICT-China project manager, Institute of Cancer Therapeutics , University of Bradford - 2006 to 2008
Postdoctoral Research Fellow, Institute of Neuroscience, University of Newcastle - 2004 to 2006
Visiting Scientist, School of Biomedical Sciences, University of Nottingham - 2000 to 2000
Pharmacologist/Senior Pharmacologist/Pharmacist, Department of Pharmacology, Hebei Medicine Control Institute, a subsector of SFDA - 1988 to 2000
Teaching
Modules taught at XJTLU: Cellular and Molecular Biology; Experimental Design and Analysis; Biochemical Methods and Analysis; Cell Structure and Function; Molecular Biology Principle; Molecular and Cell Biology Techniques; Advanced Biochemical Methods; Final Year Project.
Modules taught in the UK University: Introduction to Biochemistry; Cellular and Biochemical Basis of Pharmacology; Investigation of Diseases; System Pharmacology; CNS, Pain and Cancer Therapy; Cancer Biology
Courses at XJTLU: Biological Sciences (UG); Bioinformatics (UG): Molecular Bioscience (MRes); Biopharmaceutical (UG); Pharmaceutical Sciences (UG)
Courses in the UK university: Pharmacy(UG); Biomedical Sciences (UG); Cancer Biology (MRes)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Ph.D. , Neuropharmacology, University of Bradford, UK - 2004
M.Sc. , Pharmacology, Hebei Medical University, China - 1997
B.Sc. , Pharmacy, Hebei Medical University, China - 1988
M.A. , Teaching and learning in higher education, University of Central Lancashire, UK- 2012
Research areas
- Migraine pathogenesis
- signal transduction
- Src family kinases
- Stress
- TRP channels
Person Types
- Staff
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Collaborations and top research areas from the last five years
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Uncovering New Therapeutic Targets Through Omics Analysis in Complementary Mouse Models for Improved Efficacy
1/03/25 → 29/02/28
Project: Other
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The role of epigenetic histone H3 modifications in regulating neuroinflammation in the rodent model of migraine
1/03/23 → 28/02/26
Project: Other
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Suzhou Municipal Key Lab for Metabolic Syndrome Drug Research
Meng, J., Meng, W., Jiang, X., Wei, Z., Li, T., Liu, X., Su, J., Yue, C., Douroudis, K., Kappes, F., Park, J., Wang, M., Rong, R., Raju, S., Huang, X., Kadowaki, T., OConnor, D., Lu, Z., Feng, Q., Yi, Y., Chen, Y., Jiang, B., Yuan, X., Cui, J., Meng, S., Smith, G., Loh, B. & 李荪
1/01/22 → 31/12/23
Project: Governmental Research Project
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Identification of drug targets involved in TRPA1 signaling for preventing classical migraine
Wang, M., Wang, M., Kappes, F., Quinn, J., 蒋莉文, 马冬青, 聂聆俤 & 鲁德意
1/07/18 → 30/06/21
Project: Internal Research Project
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Modulating the excitation/inhibition balance by astrocytes with a tripartite synapse model of Alzheimer's disease
Li, J., Liu, J. K., Zaikin, A., Wang, M. & Chen, S., Aug 2025, (Accepted/In press) In: Neural Regeneration Research.Research output: Contribution to journal › Article › peer-review
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Nuclear paraspeckle assembly transcript 1 promotes photophobia behavior in mice via miR-196a-5p/Trpm3 coupling
Huang, Z., Li, X., Wang, X., Wu, J., Gong, Z., Kõks, S. & Wang, M., May 2025, In: Journal of Headache and Pain. 26, 1, 118.Research output: Contribution to journal › Article › peer-review
Open Access -
Gender-different effect of Src family kinases antagonism on photophobia and trigeminal ganglion activity
Huang, Z., Yao, J., Nie, L., Nie, X., Xiong, X., Koks, S., Quinn, J. P., Kanhere, A. & Wang, M., Oct 2024, In: Journal of Headache and Pain.Research output: Contribution to journal › Article › peer-review
Open Access -
Src family kinases (SFKs) in Migraine
Wang, M., Gong, Z. & Huang, Z., 24 Oct 2024, Migraine Pain Management: Current Pharmacological and Non-pharmacological Options. Shrewsbury, S. B. (ed.). 1st Edition ed. Elsevier, Vol. In Part II: Druggable targets.Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review
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Src Family Kinases Facilitate the Crosstalk between CGRP and Cytokines in Sensitizing Trigeminal Ganglion via Transmitting CGRP Receptor/PKA Pathway
Nie, L., Sun, K., Gong, Z., Li, H., Quinn, J. P. & Wang, M., Oct 2024, MDPI (Basel, Switzerland) . (Migraine Neuroscience: From Experimental Models to Target Therapy)Research output: Book/Report/Edited volume › Anthology › peer-review
Activities
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22nd International Headache Congress
Minyan Wang (Speaker)
10 Sept 2025 → 13 Sept 2025Activity: Talk or presentation › Presentation at conference/workshop/seminar
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Invited speaker at 2025 CBA-China annual congress
Minyan Wang (Speaker)
27 Jun 2025 → 28 Jun 2025Activity: Talk or presentation › Invited talk
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Research Progress and Market Prospects Analysis of Innovative Migraine Drugs
Minyan Wang (Speaker)
24 Jun 2025 → 25 Jun 2025Activity: Talk or presentation › Invited talk
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TRPA1 in migraine pathogenesis and advances in targeted drug therapy
Minyan Wang (Speaker)
16 May 2025Activity: Talk or presentation › Invited talk
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Chinese Headache Congress
Minyan Wang (Participant)
16 May 2025 → 18 May 2025Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …